Which biosafety level requires the use of specific training in handling pathogens?

Biosafety Level 2 (BSL-2) is the correct answer because it specifically pertains to laboratory practices involving moderate-risk pathogens that can cause disease in humans. The handling of these pathogens requires specific training to ensure that laboratory personnel are aware of the risks and know how to mitigate them through proper techniques and safety protocols.

At this level, when working with agents that present a moderate risk to personnel and the environment, it is essential for researchers and technicians to understand how to safely manage their work. This includes wearing appropriate personal protective equipment (PPE), implementing waste disposal procedures, and being familiar with exposure response strategies.

Lower biosafety levels, like BSL-1, do not necessitate specialized training beyond standard laboratory practices since they involve well-characterized agents that rarely cause disease in healthy individuals. BSL-3 and BSL-4 levels, while also requiring specialized training, pertain to high-risk biological agents that necessitate more complex safety measures and equipment. However, the training specifically related to handling pathogens and their specific risks begins at BSL-2, making it the most appropriate choice in this context.